1 2 1 Na – Ca exchanger isoforms in rat neuronal preparations : different changes in their expression during postnatal development
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چکیده
1 21 We examined the relative amounts of Na –Ca exchanger (NCX) isoform mRNAs in cultured neurons, astrocytes and developmental rat brain. NCX1 transcript was predominant in neurons and astrocytes, but NCX2 transcript was about four-fold higher than NCX1 or NCX3 transcript in adult rat cortex. NCX2 transcript in the cortex increased markedly during postnatal development, whereas NCX1 and 1 45 21 NCX3 transcripts decreased. Na -dependent Ca uptake in the cortical homogenate increased significantly during postnatal development. 2000 Elsevier Science B.V. All rights reserved. Theme: Neurotransmitters, modulators, transporters and receptors Topic: Uptake and transporters 1 21
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تاریخ انتشار 2000